Microcytic Anemias
Iron deficiency, thalassemia, anemia of chronic disease, sideroblastic, lead.
Macrocytic + Normocytic Anemias
B12 vs folate, hypersegmented neutrophils, and the PNH that hides as both.
Iron Deficiency Anemia Workup
Ferritin, TIBC, transferrin saturation. The iron studies that nail IDA.
Anemias
Hemolytic Anemias: Intravascular vs Extravascular
Coagulation + Bleeding Disorders
Hemophilia, vWD, vitamin K deficiency. PT vs PTT and the factor that explains it.
Drugs of the Clotting Cascade
Heparin, warfarin, DOACs, tPA. Anticoagulants and thrombolytics by mechanism.
Hemophilia + the Coag Cascade
Factor VIII vs IX, X-linked recessive, and the joint bleeds that define hemophilia.
Platelets + Hemostasis
Quantitative vs qualitative defects. ITP, TTP, HUS, and the bleeding-time / PT / PTT panel that sorts them out.
Platelet Plug + Platelet Disorders
Adhesion, activation, aggregation. ITP, TTP, HUS, and the qualitative defects.
Coagulation Cascade
Bleeding and Coagulation Disorder Decoder
Hemophilic Arthropathy and Hemarthrosis
Multiple Myeloma & MGUS
CRAB criteria, M-spike on SPEP, and lytic bone lesions. MGUS vs smoldering vs symptomatic myeloma.
Leukemias: ALL vs AML vs CLL vs CML
Lead Poisoning
Chromosomal Translocations
Chromosomal Translocations in Hematologic Malignancies: t(9;22), t(14;18), t(8;14), t(11;14), t(15;17), t(11;22). Match game, flip cards, elimination, board walkthrough.