The Big 5 Autoimmune Diseases
SLE vs RA vs Scleroderma vs Dermatomyositis vs Sjogren's. Battle cards, antibody matching game, diagnostic decision tree, 10-question quiz pool.
Autoantibodies & Drug-Induced Lupus
Hypersensitivity Reactions
Types I-IV, IgE vs IgG vs T-cells, timing, classic diseases, board traps. Drag-drop type sorter + elimination game + 12-question pool.
Primary Immunodeficiency Disorders 🔒
The Big 10: Bruton's, SCID, DiGeorge, CGD, Wiskott-Aldrich, CVID, Hyper-IgM, Chediak-Higashi, IgA deficiency, complement. Disease cards, drag-drop sorting, decision tree, elimination game + 14-question pool.
Vasculitides 🔒
12 inflamed vessels organized by size. Takayasu, GCA, PAN, Kawasaki, GPA, MPA, EGPA, HSP, Behçet, Buerger. Vessel-size tabs + sorting game + 9-question quiz pool.
Free Radicals & NADPH Oxidase
How neutrophils make bleach (HOCl) to kill bacteria, why CGD patients can't, and the catalase-positive organisms that exploit the gap. Pathway stepper, elimination game, villain flip cards, 8-question pool.
The Complement System: C3b, Factor H, and the Cascade
Complement Deficiencies: HAE, PNH, aHUS and the Neisseria Trap
Immune Cell Lineage: Hematopoiesis From Stem Cell to Every Immune Cell
The Lymphatic System: Organs, Histology and Drainage 🔒
Anaphylaxis
IgE mast-cell release, IM epinephrine first, and the biphasic trap.