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COMLEX · USMLE

Pharmacology

Mechanisms, side effects, drug interactions, and the antidotes boards love.

Autonomic
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Beta-Blockers 🔒

Selective vs non-selective, ISA, and the post-MI cardioprotection rule.

HIGH YIELDbetablockers
Walk the Nephron — Diuretics
Cardiovascular & Renal
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Hypothalamic & Pituitary Drugs FREE

Pulsatile GnRH builds. Continuous GnRH destroys. That paradox is question one. Then: somatostatin for carcinoid crisis, cabergoline for prolactinoma, DDAVP for central DI, vaptans for SIADH. Every hypothalamic axis mapped to its drug.

HIGH YIELDhypothalamicpituitarydrugs
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Digoxin · Bone Wizardry FREE

Block the pump. Flood the cell. Save the heart. The drug that poisons the Na/K-ATPase on purpose · and somehow that makes the heart squeeze harder.

HIGH YIELDdigoxinbonewizardry
Endocrine
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Antidiabetic Drug Classes 🔒

Metformin, sulfonylureas, GLP-1, SGLT2. Mechanism and the side effect that defines each.

HIGH YIELDantidiabeticdrugclasses
Anti-Infective
Toxicology & Drug Reactions
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Tyramine Crisis: the cheese reaction 🔒

Hypertensive crisis on MAOIs. Mechanism, forbidden foods, phentolamine first-line, and the serotonin-syndrome trap.

HIGH YIELDtyraminecrisischeesereaction
Alpha Blockers
More
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Prostate Cancer Drugs FREE

Five drug classes, five hit points on the HPG axis. GnRH agonists flood the signal to cause a drought. Antagonists cut straight to castration. Abiraterone kills the adrenal backup. AR blockers take the last stand. Docetaxel ends the cell cycle.

HIGH YIELDprostatecancerdrugs
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6-MP, Allopurinol & Antimetabolites FREE

HIGH YIELDallopurinolantimetabolites
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