Pharmacology

Selective vs non-selective, ISA, and the post-MI cardioprotection rule.

Pulsatile GnRH builds. Continuous GnRH destroys. That paradox is question one. Then: somatostatin for carcinoid crisis, cabergoline for prolactinoma, DDAVP for central DI, vaptans for SIADH. Every hypothalamic axis mapped to its drug.

Metformin, sulfonylureas, GLP-1, SGLT2. Mechanism and the side effect that defines each.

Hypertensive crisis on MAOIs. Mechanism, forbidden foods, phentolamine first-line, and the serotonin-syndrome trap.

Interactive anesthesia pharmacology review: local anesthetic sodium-channel blockade, amides and esters, epinephrine, acidic tissue, methemoglobinemia, bupivacaine cardiotoxicity, succinylcholine, nondepolarizing blockers, and malignant hyperthermia.

Interactive board review of general anesthetics: blood:gas onset, oil:gas potency, MAC, volatile anesthetic toxicity, malignant hyperthermia, nitrous oxide air-space expansion, and IV induction agents.

Five drug classes, five hit points on the HPG axis. GnRH agonists flood the signal to cause a drought. Antagonists cut straight to castration. Abiraterone kills the adrenal backup. AR blockers take the last stand. Docetaxel ends the cell cycle.

Autonomic nervous system pharmacology for medical students: somatic versus autonomic wires, sympathetic and parasympathetic receptor maps, adrenal medulla and sweat gland exceptions, organ effects, and clinical walkthroughs.