Title: Big Ol' Bonewizardry Deck / Hex Clues / Pharm
Tags: hex-clues hex-clues::pharm

Q: How do you treat CO poisoning?
A: 100% O2 🎯
kicks CO off Hb 🩸🧬
hyperbaric if severe 🔵

Q: How do you treat Pb poisoning?
A: Lead poisoning Tx 🎯
succimer (kids) 🎯
EDTA / dimercaprol if severe adult ⚙️

Q: How do you treat Warfarin overdose?
A: Vitamin K (slow) 🥬💉
FFP / PCC if bleeding 💉

Q: How do you treat Fe overdose?
A: Iron OD Tx ⚙️🩸
deferoxamine (acute) 🎯
deferasirox (chronic) ⚙️

Q: How do you treat Opioid overdose?
A: naloxone 🎯
mu-receptor antagonist 🥊

Q: How do you treat β-blocker overdose?
A: glucagon 🎯
bypasses β-receptor → ↑cAMP 🔀

Q: What drugs can be Hepatotoxic?
A: fat-soluble 🎯
acetaminophen + statins + INH + valproate + amiodarone 🍺

Q: How do you treat Cyanide poisoning?
A: amyl nitrite + Na thiosulfate 🎯
or hydroxocobalamin 💉

Q: How do you treat Nitrite overdose?
A: methylene blue 🎯
reduces methemoglobin → Hb 🩸

Q: What do opioid kappa receptors cause?
A: spinal level 🎯
analgesia + dysphoria / sedation 😴

Q: What drugs can be Nephrotoxic?
A: water-soluble 🎯
aminoglycosides + vanc + NSAIDs + contrast + cisplatin 💧

Q: How do you treat Benzodiazepine overdose?
A: Benzo OD Tx 🎯
flumazenil 🎯
GABA-A antagonist + risk of seizures ⚡

Q: How do you treat Heparin overdose?
A: protamine sulfate 🎯
positive charge binds heparin ➕

Q: What do opioid mu receptors cause?
A: analgesia + respiratory depression 🎯
euphoria + miosis (pinpoint pupils) 👁️

Q: What drugs dilate veins and arteries?
A: ACE-I + Nitrates 🎯
balanced venous + arterial dilation 📡🔬
both V and A 🌬️

Q: What is the 1-dose treatment for Chlamydia?
A: azithromycin 1 g PO ×1 🎯
or doxy 7 days 💉

Q: How do you treat Acetaminophen overdose?
A: APAP OD Tx 🎯
N-acetylcysteine 🧪🛡️
replenishes glutathione 🛡️

Q: How do you treat Fibrinolytic overdose?
A: aminocaproic / tranexamic acid 🎯
inhibits plasminogen activation 🛑

Q: How do you treat CCB overdose?
A: calcium chloride + glucagon 🎯
± insulin / glucose 💉

Q: What are the intermediate-acting DM Type 1 drugs?
A: Intermediate-acting insulin 🎯
peak 4-10 hr 🎯
NPH + Lente ⏱️

Q: How do you treat Salicylate overdose?
A: charcoal + bicarb 🎯
alkalinize urine + dialysis if severe 🚽

Q: What are the long-acting DM Type 1 drugs?
A: Long-acting insulin 🎯
basal ~24 hr no peak 🎯
glargine + detemir + ultralente 🌙

Q: How do you treat Lithium overdose?
A: hemodialysis 🎯
avoid NSAIDs / thiazides 🎯
Na polystyrene if mild ⚠️

Q: What drugs cause dysgeusia?
A: metallic taste 🎯
metronidazole + clarithromycin + lithium 🪙

Q: What are the short-acting DM Type 1 drugs?
A: Short-acting insulin 🎯
mealtime / bolus 📡🔬
lispro + regular + aspart + glulisine 🍽️

Q: How do you treat TCA overdose?
A: sodium bicarbonate 🧂⚡
narrows QRS + prevents arrhythmias 📉

Q: How do you treat Ethylene Glycol, MeOH overdose?
A: EG / MeOH OD Tx 🎯
fomepizole (or EtOH) 🎯
inhibits alcohol dehydrogenase 🛑

Q: What drugs act as haptens on platelets?
A: drug-induced thrombocytopenia 🩸🟣
aspirin + heparin (HIT) + quinidine 🎯

Q: How do you treat Organophosphate poisoning?
A: OP poisoning Tx 🎯
atropine + pralidoxime 🎯
anti-muscarinic + regenerates AChE 🪖

Q: What antibody is associated with drug-induced lupus?
A: Anti-histone Ab 🛡️🎯
drug-induced lupus marker 📡🔬
SLE pattern 🩺

Q: What drugs wipe out granulocytes?
A: Agranulocytosis drugs 🎯
granulocyte wipeout 🎯
carbamazepine + clozapine + ticlopidine + methimazole + PTU ⚠️

Q: How do you treat Cu, Gold, Cd, Mercury, Arsenic poisoning?
A: Heavy metal Tx 🎯
penicillamine 🎯
dimercaprol for arsenic / mercury ⚙️

Q: What bugs are treated with vancomycin?
A: Vancomycin coverage 💊⚔️
Gram + only 🦠🟣
MRSA + S. epi + enterococcus + C. diff (oral) 🎯

Q: What drugs cause disulfiram reactions?
A: Disulfiram-like drugs 🎯
flushing + vomit with EtOH 🤮💧
metronidazole + cephalosporins + procarbazine + 1st-gen sulfonylureas 🤢

Q: What drugs cause SLE?
A: Drug-induced SLE 🎯
HIPPPE mnemonic 🎯
Hydralazine + INH + Procainamide + Phenytoin + Penicillamine + Ethosuximide ⚠️

Q: What antibiotics are in a triple antibiotic?
A: Brand New Patient mnemonic 🎯
Bacitracin + Neomycin + Polymyxin 🩺

Q: What drugs have sulfur in them?
A: Sulfa-containing drugs 🎯
sulfa allergy risk 🎯
ACEI + celecoxib + loops + thiazides + sulfonylureas + sulfonamides ⚠️

Q: How do you treat Theophylline overdose?
A: charcoal + esmolol 🎯
benzo / barb for seizures ⚡